Accelerating advances in early psychosis care, recovery outcomes, and scientific discovery through a national early psychosis learning health care partnership


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Principal Investigators:

Sophia Vinogradov, MD

Piper Meyer-Kalos, PhD


EPI-MINN consists of six Coordinated Specialty Care (CSC) teams across the state of Minnesota. EPI-MINN’s goal is to help CSC teams expand measurement-based care by implementing measures of symptoms, functioning, and cognition using state-of-the-art digital platforms. Clinicians will deliver assessment results to clients, along with personalized feedback using graphical reports to inform treatment-making decisions. In addition, EPI-MINN will offer clients the opportunity to enroll in a randomized controlled trial to examine mobile cognitive training and motivation enhancement applications embedded in CSC, compared to treatment as usual.

click to see a list of EPI-MINN clinics

See the full list of EPI-MINN clinics

A multi-ethnic group of six high school students, 15 to 17 years old, standing together in a library conversing. They are all looking toward the African-American girl on the right, smiling. The girl in the middle is mixed race Hispanic and Caucasian.


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  • Measurement Based Care (MBC): Conducting observational and longitudinal assessments of symptoms, functioning, and cognition using an online platform.
  • Feedback Visit: Providing clients personalized interpretations of the MBC data that emphasize strengths and discuss areas for work.
  • Cognitive and Social Cognitive Training, BrainHQ: Offering 30 hours of remote cognitive training including auditory and social cognition training.
  • Personalized Real-Time Motivational Enhancement (PRIME) App: Using a smartphone-based app to enhance client motivation, work towards self-identified goals, connect with a virtual community of peers, and engage clients with motivation coaches.
  • Integrated Individual Resiliency Training (IRT): Evaluating the need for cognitive strategies during the early stages of goal setting and follow through. IRT therapists integrate the cognitive information with treatment and goal-planning, and collaboratively select and teach cognitive self-management strategies to overcome cognitive challenges to goal attainment.

Contact Information

EPI-MINN website

University of Minnesota Riverside
(Strengths and Early Stage Mood Disorders)

Human Development Center

St. Louis Park Clinic NAVIGATE Programs

Hennepin Healthcare HOPE Clinic

EPI-MINN Clinics

Human Development Center Comprehensive Behavioral HealthcareOpens a new tab
Duluth, MN

Riverside Strengths Program Adult ProgramOpens a new tab
Riverside Strengths Program Adolescent ProgramOpens a new tab
Riverside Early Stage Mood Disorders Program
Minneapolis, MN

The HOPE ProgramOpens a new tab
Minneapolis, MN

St. Louis Park Clinic Navigate ProgramOpens a new tab
Saint Louis Park, MN

EPI-MINN is supported by the National Institute of Mental Health under award number R01MH120589.

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